【论著】低分子肝素钙治疗抗心磷脂抗体所致的流产

  09-06-15  

摘要目的探讨低分子肝素钙治疗抗心磷脂抗体所致流产的疗效。方法将206例抗心磷脂抗体阳性患者，确诊妊娠后随机分为两组，各103例，分别给予低分子肝素钙（肝素组）和小剂量阿司匹林加强的松（传统组），观察两组抗体转阴率及妊娠结局。结果肝素组抗体转阴率78.6%，活产率92.2%；传统组转阴率54.4%，活产率76.6%，差异有统计学意义。结论低分子肝素钙治疗抗心磷脂抗体所致的流产效果显著。
关键词低分子肝素抗心磷脂抗体流产
Low molecular weight heparin calcium treat the abortions caused by anticardiolipin antibodies
ZHANG Junli
ABSTRACTObjectiveTo inquire the curative effect of low molecular weight heparin in the treatment of abortion caused by anticardiolipin antibodies（ACA）. MethodsThere are 206 patients with ACA positive and pregnancy. They were devided  into two groups equally. The patients of the first group were treated in low molecular weight heparin calcium, yet the another group were treated in asprin and prednisone. Then the turnnegativerate of ACA and the perinatal outcome were observed. ResultsIn heparin group, ACA turnnegativerate was 78.6%, newbron alive rate was 92.2%. Another group, turnnegativerate was 54.4%, newbron alive rate was 76.6%, there were significant differences between two groups. ConclusionLow molecular weight heparin calcium could be used to treated in abortion caused by ACA.
KEY WORDSLow molecular weight heparin calciumAnticardiolipin antibodies（ACA）Abortion

作者单位天津市宝坻区人民医院